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Watch Carefully (1)pentobarbital will lessen the level or influence of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.Contraindicated (one)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can cut down panobinostat amounts by ~70%